Congratulations to Matt for successfully defending his PhD dissertation entitled “Trauma-Induced Alterations of Cerebral Vessel Mechanics and Microstructure.”...
Continue readingPaper on collagen damage in blood vessels accepted by Acta Biomaterialia
Congratulations to Matt and co-authors for acceptance of our paper entitled “Detection and characterization of molecular-level collagen damage in overstretched cerebral arteries” for publication in Acta Biomaterialia! This paper reports the first identification and quantification of collagen damage in blood vessels following overstretch using the novel collagen hybridizing peptide (CHP) invented by the Michael Yu laboratory...
Continue readingAbhidnya successfully defends her MS thesis
Congrats to Abhidnya for defending her MS thesis entitled “Study of Change of Orientation of Adventitial Collagen in Cerebral Blood Vessels During and After Axial Overstretch.”...
Continue readingSameer successfully defends his MS thesis
Congratulations to Sameer for successfully defending his MS thesis entitled “Computational Characterization of Vascular Mechanics”! Sameer used computational modeling to explore vessel mechanics in both ring and high-rate testing....
Continue readingNew funding from Henry Jackson Foundation
The lab has received notice of new funding from the Henry Jackson Foundation, through collaboration with the Biotechnology HPC Software Applications Institute, to investigate the high-rate properties of minipig brain and cerebral arteries. Findings will be used to develop of a model of blast brain injury....
Continue readingMatt takes 1st place at SB3C!
Congrats to Matt for taking first place in the student paper competition at SB3C in Tucson on June 24! The title of his presentation was “Arterial damage model based on empirical stretch thresholds of collagen unfolding and tissue yielding.” This work utilizes data on collagen fiber unfolding in overstretched vessels to inform a theoretical...
Continue readingStewart successfully defends dissertation
Congratulations to Dr. Yeoh for successfully defending his disseration and finishing up his PhD! The title of his dissertation is “Cerebrovascular Dysfunction in Primary Blast Traumatic Brain Injury.”...
Continue readingStretch-induced dysfunction paper accepted
Congratulations to Dave and to our collaborator Tony Donato for acceptance of our paper entitled “Cerebrovascular dysfunction following subfailure axial stretch” for publication in the Journal of the Mechanical Behavior of Biomedical Materials! This paper reports experiments showing that smooth muscle contractile response is altered by sub-failure axial overstretch. This suggests that tissue deformation during...
Continue readingCerebral artery development paper accepted
Congratulations to Kevin, Matt, and our collaborators in the Albertine Lab, on the acceptance of our paper entitled “Development of mechanical and failure properties in sheep cerebral arteries” by the Annals of Biomedical Engineering! This research shows dramatic changes in the large deformation response of cerebral arteries between late gestation and adulthood. See publications page for more details....
Continue readingWill Anderl awarded UROP for Fall 2016
Congratulations to Will for being selected for participation in the Undergraduate Research Opportunities Program for the Fall 2016 semester! As part of this research, he will investigate cerebral vessel wall collagen fiber damage in traumatic brain injury....
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