Congrats to Will and Noah for recent acceptance of their paper “Strain-induced collagen denaturation is rate dependent in failure of cerebral arteries” at Acta Biomaterialia! This research shows that the extent of collagen molecule damage decreases with strain rate when vessels are stretched to failure. Collaborators include Matt Converse and Michael Yu....
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Soon-to-be Dr. Noah Pearson successfully defended his dissertation, titled “High Strain Rate Damage in Cerebral Arteries: A Molecular and Mechanical Analysis”!...
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Congratulations to Noah for getting his paper entitled “A strain-rate dependent constitutive model for Göttingen minipig cerebral arteries” published in the Journal of Biomechanical Engineering! This paper shows that Göttingen minipig cerebral arteries are rate dependent and proposes a model for use in computational models of head injury that account for the vasculature. See the publications...
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Congratulations to Matt and Kevin for getting their paper entitled “Stretch-induced intimal failure in isolated cerebral arteries as a function of development” published in Annals of Biomedical Engineering! This paper shows that the intimal layer of cerebral arteries commonly ruptures prior to external layers and may have significant implications for vessel dysfunction following traumatic brain...
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Congratulations to Matt for getting his paper entitled “Biaxial softening of isolated cerebral arteries following axial overstretch” accepted for publication at the Journal of the Mechanical Behavior of Biomedical Materials. This paper quantifies changes in circumferential properties following overstretch. See the publications page for more details....
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Congrats to Farshad Mogharrabi for successfully defending his MS thesis! It is titled “Experimental evaluation of photo-activated cross-linking effects on mechanical properties of arteries post-angioplasty.” This work was performed in collaboration with Alucent Biomedical....
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Congratulations to Dave and co-authors for acceptance of our paper entitled “Material properties of rat middle cerebral arteries at high strain rates.” It will be published in the Journal of Biomechanical Engineering. This paper details the strain rate dependence of rat cerebral artery properties. See publications page for more details....
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Congratulations to Matt for successfully defending his PhD dissertation entitled “Trauma-Induced Alterations of Cerebral Vessel Mechanics and Microstructure.”...
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Congratulations to Matt and co-authors for acceptance of our paper entitled “Detection and characterization of molecular-level collagen damage in overstretched cerebral arteries” for publication in Acta Biomaterialia! This paper reports the first identification and quantification of collagen damage in blood vessels following overstretch using the novel collagen hybridizing peptide (CHP) invented by the Michael Yu laboratory...
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Congrats to Abhidnya for defending her MS thesis entitled “Study of Change of Orientation of Adventitial Collagen in Cerebral Blood Vessels During and After Axial Overstretch.”...
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