Paper on stretch-induced rupture of intima published

Congratulations to Matt and Kevin for getting their paper entitled “Stretch-induced intimal failure in isolated cerebral arteries as a function of development” published in Annals of Biomedical Engineering! This paper shows that the intimal layer of cerebral arteries commonly ruptures prior to external layers and may have significant implications for vessel dysfunction following traumatic brain...

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Paper on collagen damage in blood vessels accepted by Acta Biomaterialia

Congratulations to Matt and co-authors for acceptance of our paper entitled “Detection and characterization of molecular-level collagen damage in overstretched cerebral arteries” for publication in Acta Biomaterialia! This paper reports the first identification and quantification of collagen damage in blood vessels following overstretch using the novel collagen hybridizing peptide (CHP) invented by the Michael Yu laboratory...

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Stretch-induced dysfunction paper accepted

Congratulations to Dave and to our collaborator Tony Donato for acceptance of our paper entitled “Cerebrovascular dysfunction following subfailure axial stretch” for publication in the Journal of the Mechanical Behavior of Biomedical Materials! This paper reports experiments showing that smooth muscle contractile response is altered by sub-failure axial overstretch. This suggests that tissue deformation during...

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