Congrats to Will and Noah for recent acceptance of their paper “Strain-induced collagen denaturation is rate dependent in failure of cerebral arteries” at Acta Biomaterialia! This research shows that the extent of collagen molecule damage decreases with strain rate when vessels are stretched to failure. Collaborators include Matt Converse and Michael Yu....
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Soon-to-be Dr. Noah Pearson successfully defended his dissertation, titled “High Strain Rate Damage in Cerebral Arteries: A Molecular and Mechanical Analysis”!...
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Congratulations to Noah for getting his paper entitled “A strain-rate dependent constitutive model for Göttingen minipig cerebral arteries” published in the Journal of Biomechanical Engineering! This paper shows that Göttingen minipig cerebral arteries are rate dependent and proposes a model for use in computational models of head injury that account for the vasculature. See the publications...
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Congratulations to Matt and Kevin for getting their paper entitled “Stretch-induced intimal failure in isolated cerebral arteries as a function of development” published in Annals of Biomedical Engineering! This paper shows that the intimal layer of cerebral arteries commonly ruptures prior to external layers and may have significant implications for vessel dysfunction following traumatic brain...
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The lab has received notice of new funding from the National Science Foundation. The goals of this project are to define rate-dependent, multiscale damage mechanisms in blood vessels and to link these mechanisms to changes in vessel properties through a constitutive damage model....
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Congratulations to Dave and co-authors for acceptance of our paper entitled “Material properties of rat middle cerebral arteries at high strain rates.” It will be published in the Journal of Biomechanical Engineering. This paper details the strain rate dependence of rat cerebral artery properties. See publications page for more details....
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Our review article entitled “Cerebral blood vessel damage in traumatic brain injury” has been accepted for publication in Clinical Biomechanics. This paper outlines the current state of knowledge on vascular damage in traumatic brain injury....
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