Soon-to-be Dr. Noah Pearson successfully defended his dissertation, titled “High Strain Rate Damage in Cerebral Arteries: A Molecular and Mechanical Analysis”!...
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Paper reporting model for rate dependent cerebral vasculature published
Congratulations to Noah for getting his paper entitled “A strain-rate dependent constitutive model for Göttingen minipig cerebral arteries” published in the Journal of Biomechanical Engineering! This paper shows that Göttingen minipig cerebral arteries are rate dependent and proposes a model for use in computational models of head injury that account for the vasculature. See the publications...
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Paper on stretch-induced rupture of intima published
Congratulations to Matt and Kevin for getting their paper entitled “Stretch-induced intimal failure in isolated cerebral arteries as a function of development” published in Annals of Biomedical Engineering! This paper shows that the intimal layer of cerebral arteries commonly ruptures prior to external layers and may have significant implications for vessel dysfunction following traumatic brain...
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Paper on biaxial softening accepted for publication
Congratulations to Matt for getting his paper entitled “Biaxial softening of isolated cerebral arteries following axial overstretch” accepted for publication at the Journal of the Mechanical Behavior of Biomedical Materials. This paper quantifies changes in circumferential properties following overstretch. See the publications page for more details....
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Farshad successfully defends MS thesis
Congrats to Farshad Mogharrabi for successfully defending his MS thesis! It is titled “Experimental evaluation of photo-activated cross-linking effects on mechanical properties of arteries post-angioplasty.” This work was performed in collaboration with Alucent Biomedical....
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New funding from the NSF
The lab has received notice of new funding from the National Science Foundation. The goals of this project are to define rate-dependent, multiscale damage mechanisms in blood vessels and to link these mechanisms to changes in vessel properties through a constitutive damage model....
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Paper on rat cerebral artery rate dependence accepted by Journal of Biomechanical Engineering
Congratulations to Dave and co-authors for acceptance of our paper entitled “Material properties of rat middle cerebral arteries at high strain rates.” It will be published in the Journal of Biomechanical Engineering. This paper details the strain rate dependence of rat cerebral artery properties. See publications page for more details....
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Review article on vessel biomechanics in TBI accepted for publication
Our review article entitled “Cerebral blood vessel damage in traumatic brain injury” has been accepted for publication in Clinical Biomechanics. This paper outlines the current state of knowledge on vascular damage in traumatic brain injury....
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Matt successfully defends dissertation
Congratulations to Matt for successfully defending his PhD dissertation entitled “Trauma-Induced Alterations of Cerebral Vessel Mechanics and Microstructure.”...
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Paper on collagen damage in blood vessels accepted by Acta Biomaterialia
Congratulations to Matt and co-authors for acceptance of our paper entitled “Detection and characterization of molecular-level collagen damage in overstretched cerebral arteries” for publication in Acta Biomaterialia! This paper reports the first identification and quantification of collagen damage in blood vessels following overstretch using the novel collagen hybridizing peptide (CHP) invented by the Michael Yu laboratory...
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